Justification of sexual reproduction by modified Penna model of ageing

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Justification of Sexual Reproduction by Modified Penna Model of Ageing

We generalize the standard Penna bit-string model of biological ageing by assuming, that each deleterious mutation diminishes the survival probability in every time interval by a small percentage. This effect is added to the usual lethal but age-dependent effect of the same mutation. We then find strong advantages or disadvantages of sexual reproduction (with males and females) compared to asex...

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Gamete recognition and complementary haplotypes in sexual Penna ageing model

In simulations of sexual reproduction with diploid individuals, we introduce that female haploid gametes recognize one specific allele of the genomes as a marker of the male haploid gametes. They fuse to zygotes preferrably with male gametes having a different marker than their own. This gamete recognition enhances the advantage of complementary bit-strings in the simulated diploid individuals,...

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Love kills Penna ageing model

Love may have been a female invention long ago, when the brain of genus homo became large and required more food. Thus the father was needed to help feed mother and baby. Pekalski [1] assumed mate selection to be governed by a Major Histocompatibility Complex MHC. In the same spirit now the sexual Penna ageing model is modified to include mate selection by an additional string of 32 bits for ea...

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Assuming the deleterious mutations in the Penna ageing model to affect mainly the young ages, we get an enhanced mortality at very young age, followed by a minimum of the mortality, and then the usual exponential increase of mortality with age. The standard Penna ageing model, based on strings of 32 bits for each individual, gives good agreement with human mortality at middle and old age a, whe...

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Scaling Effects in the Penna Ageing Model

We have analysed the possibility of scaling the sexual Penna ageing model. Assuming that the number of genes expressed before the reproduction age grows linearly with the genome size and that the mutation rate per genome and generation is constant, we have found that the fraction of defective genes expressed before the minimum reproduction age drops with the genome size, while the number of def...

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ژورنال

عنوان ژورنال: Physica A: Statistical Mechanics and its Applications

سال: 2001

ISSN: 0378-4371

DOI: 10.1016/s0378-4371(01)00127-3